AG5 is a potent non-steroidal anti-inflammatory and immune regulator that preserves innate immunity

An archetypal anti-inflammatory compound against cytokine storm would inhibit it without suppressing the innate immune response. AG5, an anti-inflammatory compound, has been developed as synthetic derivative of andrographolide, which is highly absorbable and presents low toxicity. We found that the...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2023-12, Vol.169, p.115882-115882, Article 115882
Hauptverfasser:	Botella-Asunción, Pablo, Rivero-Buceta, Eva M., Vidaurre-Agut, Carla, Lama, Raquel, Rey-Campos, Magalí, Moreno, Alejandro, Mendoza, Laura, Mingo-Casas, Patricia, Escribano-Romero, Estela, Gutierrez-Adan, Alfonso, Saiz, Juan Carlos, Smerdou, Cristian, Gonzalez, Gloria, Prosper, Felipe, Argemí, Josepmaría, Miguel, Jesus San, Sanchez-Cordón, Pedro J., Figueras, Antonio, Quesada-Gomez, Jose Manuel, Novoa, Beatriz, Montoya, María, Martín-Acebes, Miguel A., Pineda-Lucena, Antonio, Benlloch, Jose María
Format:	Artikel
Sprache:	eng
Schlagworte:	Andrographolide COVID-19 Cytokine storm Dexamethasone Inflammation Innate Immunity
Online-Zugang:	Volltext
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