Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease

Aberrant dopamine (DA) signalling has been implicated in various neuropsychiatric disorders, including attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), schizophrenia, bipolar disorder (BPD) and addiction. The availability of extracellular DA is sculpted by the exocyto...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Basic & clinical pharmacology & toxicology 2024-02, Vol.134 (2), p.206-218
Hauptverfasser:	Mayer, Felix P., Stewart, Adele, Blakely, Randy D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictions Attention deficit hyperactivity disorder Autism Bipolar disorder Circuits Clearances coding variant Dopamine Dopamine D2 receptors Dopamine transporter Efflux Exocytosis Homeostasis Hyperactivity In vivo methods and tests Mental disorders neuropsychiatric disorder Neurotransmission Schizophrenia Sex sex differences Specific capacity Transgenic mice
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!