Pilot study of treatment of patients with deep infiltrative endometriosis with methotrexate carried in lipid nanoparticles

Objective Previously, lipid nanoparticles (LDE) injected in women with endometriosis were shown to concentrate in the lesions. Here, the safety and feasibility of LDE carrying methotrexate (MTX) to treat deep infiltrating endometriosis was tested. Design Prospective pilot study. Setting Perola Bying...

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Veröffentlicht in:	Archives of gynecology and obstetrics 2024-02, Vol.309 (2), p.659-667
Hauptverfasser:	Avila-Tavares, Roberta, Gibran, Luciano, Brito, Luiz Gustavo Oliveira, Tavoni, Thauany Martins, Gonçalves, Manoel Orlando, Baracat, Edmund Chada, Maranhão, Raul Cavalcante, Podgaec, Sergio
Format:	Artikel
Sprache:	eng
Schlagworte:	Dysmenorrhea Dyspareunia - drug therapy Dyspareunia - etiology Endocrinology Endometriosis Endometriosis - complications Endometriosis - drug therapy Endometriosis - pathology Female Gynecologic Endocrinology and Reproductive Medicine Gynecology Human Genetics Humans Liposomes Medicine Medicine & Public Health Methotrexate - therapeutic use Nanoparticles Obstetrics/Perinatology/Midwifery Pelvic Pain - drug therapy Pelvic Pain - etiology Pilot Projects Prospective Studies
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