POCl3/Sulfoxide-Promoted Synthesis of Indolizino[8,7-b]indoles

A mild chlorocyclization of pyrrole-tethered indoles has been realized using POCl3 as the chlorine source and tetramethylene sulfoxide as the promoter. A variety of chlorinated indolizino[8,7-b]indole derivatives have been constructed efficiently under this reaction system in moderate to good yields...

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Veröffentlicht in:Journal of organic chemistry 2023-12, Vol.88 (23), p.16400-16409
Hauptverfasser: Chen, Xiao-Hui, Li, Yun-Meng, Huang, Xiang, Cui, Hai-Lei
Format: Artikel
Sprache:eng
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