Interfering TRIB3 protects the blood brain barrier through PI3K/Akt pathway to alleviate cerebral ischemia-reperfusion injury in diabetes mellitus mice

This study aimed to treat diabetic cerebral ischemia-reperfusion injury (CI/RI) by affecting blood brain barrier (BBB) permeability and integrity. The CI/RI model in DM mice and a high glucose (HG) treated oxygen and glucose deprivation/reoxygenation (OGD/R) brain endothelial cell model were establi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemico-biological interactions 2024-01, Vol.387, p.110807-110807, Article 110807
Hauptverfasser:	Zhou, Heng-Jun, Wang, Xiao-Yi, Wang, Li-Qing, Zheng, Jie-Sheng, Zhan, Ren-Ya, Pan, Jian-Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood brain barrier Cerebral ischemia-reperfusion injury Diabetes mellitus PI3K/Akt TRIB3
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!