Snapper: high-sensitive detection of methylation motifs based on Oxford Nanopore reads

Abstract Motivation The Oxford Nanopore technology has a great potential for the analysis of methylated motifs in genomes, including whole-genome methylome profiling. However, we found that there are no methylation motifs detection algorithms, which would be sensitive enough and return deterministic...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2023-11, Vol.39 (11)
Hauptverfasser:	Konanov, Dmitry N, Babenko, Vladislav V, Belova, Aleksandra M, Madan, Arina G, Boldyreva, Daria I, Glushenko, Oksana E, Butenko, Ivan O, Fedorov, Dmitry E, Manolov, Alexander I, Krivonos, Danil V, Lazarev, Vassilii N, Govorun, Vadim M, Ilina, Elena N
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms DNA Methylation Genome, Bacterial High-Throughput Nucleotide Sequencing Methyltransferases - genetics Methyltransferases - metabolism Nanopores Sequence Analysis, DNA - methods
Online-Zugang:	Volltext
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