Potential diagnostic value of miRNAs in sexually transmitted infections

•We offer a detailed elucidation of diagnostic value of miRNAs in the context of sexually transmitted infections (STIs) while also recognizing its limitations.•A more detailed description of miRNA is provided.•The article is relatively lengthy and maintains a clear logical structure. MiRNAs are small endogenous non-coding RNAs that have been demonstrated to be involved in post-transcriptional gene silencing, regulating a number of metabolic functions in the human body, including immune response, cellular physiology, organ development, angiogenesis, signaling, and other aspects. As popular molecules that have been studied in previous years, given their extensive regulatory functions, miRNAs hold considerable promise as non-invasive biomarkers. Sexually transmitted infections(STIs) are still widespread and have an adverse effect on individuals, communities, and society worldwide. miRNAs in the regulatory networks are generally involved in their molecular processes of formation and development. In this review, we discuss the value of miRNAs for the diagnosis of STIs.