Pharmacologic inhibition of lipogenesis for the treatment of NAFLD

The hepatic accumulation of excess triglycerides is a seminal event in the initiation and progression of non-alcoholic fatty liver disease (NAFLD). Hepatic steatosis occurs when the hepatic accrual of fatty acids from the plasma and de novo lipogenesis (DNL) is no longer balanced by rates of fatty a...

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Veröffentlicht in:	Journal of hepatology 2024-02, Vol.80 (2), p.362-377
Hauptverfasser:	Esler, William P., Cohen, David E.
Format:	Artikel
Sprache:	eng
Schlagworte:	DNL Humans Lipid Metabolism Lipogenesis Lipogenesis - physiology Liver - pathology NASH Non-alcoholic Fatty Liver Disease - metabolism steatosis Triglycerides - metabolism
Online-Zugang:	Volltext
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