Genome-wide association analysis reveals the associations of NPHP4, TYW1-AUTS2 and SEMA6D for Behçet's disease and HLA-B46:01 for its intestinal involvement

Intestinal involvement in Behçet's disease (BD) is associated with poor prognosis and is more prevalent in East Asian than in Mediterranean populations. Identifying the genetic causes of intestinal BD is important for understanding the pathogenesis and for appropriate treatment of BD patients....

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Veröffentlicht in:	Digestive and liver disease 2024-06, Vol.56 (6), p.994-1001
Hauptverfasser:	Jung, Eun Suk, Ellinghaus, David, Degenhardt, Frauke, Meguro, Akira, Khor, Seik-Soon, Mucha, Sören, Wendorff, Mareike, Juzenas, Simonas, Mizuki, Nobuhisa, Tokunaga, Katsushi, Kim, Seung Won, Lee, Min Goo, Schreiber, Stefan, Kim, Won Ho, Franke, Andre, Cheon, Jae Hee
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Behcet Syndrome - genetics Behçet's disease Case-Control Studies Female Genetic Predisposition to Disease Genome-Wide Association Study Genotype HLA-B Antigens - genetics HLA-B46:01 Humans Intestinal Behçet's disease Intestinal Diseases - genetics Japan Male Middle Aged Polymorphism, Single Nucleotide Republic of Korea Semaphorins - genetics Turkey
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