Collagen V haploinsufficiency in female murine patellar tendons results in altered matrix engagement and cellular density, demonstrating decreased healing

Collagen V (Col5) is a quantitatively minor component of collagen fibrils comprising tendon, however, plays a crucial role in regulation of development and dynamic healing processes. Clinically, patients with COL5a1 haploinsufficiency, known as classic Ehlers‐Danlos Syndrome (cEDS), present with hyp...

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Veröffentlicht in:	Journal of orthopaedic research 2024-05, Vol.42 (5), p.950-960
Hauptverfasser:	Carlson, Jaclyn A., Shetye, Snehal S., Sun, Mei, Weiss, Stephanie N., Birk, David E., Soslowsky, Louis J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Count Collagen - metabolism collagen V Ehlers-Danlos Syndrome Female Haploinsufficiency healing Humans injury Male Mice Patellar Ligament tendon Tendons - metabolism
Online-Zugang:	Volltext
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