From the organ bath to the whole person: a review of human colonic motility

Motor function of the colon is essential for health. Our current understanding of the mechanisms that underlie colonic motility are based upon a range of experimental techniques, including molecular biology, single cell studies, recordings from muscle strips, analysis of part or whole organ ex vivo...

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Veröffentlicht in:ANZ journal of surgery 2024-03, Vol.94 (3), p.320-326
Hauptverfasser: Wattchow, David A, Brookes, Simon J, Spencer, Nick J, Heitmann, Paul T, De Giorgio, Roberto, Costa, Marcello, Dinning, Phil G
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container_title ANZ journal of surgery
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creator Wattchow, David A
Brookes, Simon J
Spencer, Nick J
Heitmann, Paul T
De Giorgio, Roberto
Costa, Marcello
Dinning, Phil G
description Motor function of the colon is essential for health. Our current understanding of the mechanisms that underlie colonic motility are based upon a range of experimental techniques, including molecular biology, single cell studies, recordings from muscle strips, analysis of part or whole organ ex vivo through to in vivo human recordings. For the surgeon involved in the clinical management of colonic conditions this amounts to a formidable volume of material. Here, we synthesize the key findings from these various experimental approaches so that surgeons can be better armed to deal with the complexities of the colon.
doi_str_mv 10.1111/ans.18779
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects Colon
Colon - surgery
Digestive system
Gastrointestinal Motility - physiology
Gastrointestinal tract
Human motion
Humans
Molecular biology
Motility
Muscles
Surgeons
title From the organ bath to the whole person: a review of human colonic motility
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