Overcoming biological barriers BBB/BBTB by designing PUFA functionalised lipid-based nanocarriers for glioblastoma targeted therapy

A major obstacle for chemotherapeutics in Glioblastoma (GB) is to reach the tumour cells due to the presence of the blood-brain barrier (BBB) and chemoresistance of anticancer drugs. The present study reports two polyunsaturated fatty acids, gamma-linolenic acid (GLA) and alpha-linolenic acid (ALA)...

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Veröffentlicht in:	Biomaterials advances 2023-12, Vol.155, p.213660-213660, Article 213660
Hauptverfasser:	Zwain, Tamara, Alder, Jane Elizabeth, Zwayen, Suha, Shaw, Andrew, Burrow, Andrea J., Singh, Kamalinder K.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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