Meta-analysis of single-cell RNA-sequencing data for depicting the transcriptomic landscape of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by airflow limitation and chronic inflammation of the lungs that is a leading cause of death worldwide. Since the complete pathological mechanisms at the single-cell level are not fully understood yet, an integrative...

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Veröffentlicht in:	Computers in biology and medicine 2023-12, Vol.167, p.107685-107685, Article 107685
Hauptverfasser:	Lee, Yubin, Song, Jaeseung, Jeong, Yeonbin, Choi, Eunyoung, Ahn, Chulwoo, Jang, Wonhee
Format:	Artikel
Sprache:	eng
Schlagworte:	Air flow Alveoli Annotations Cells Chronic obstructive pulmonary disease Datasets Etiology Gene expression Gene sequencing Health care Humans Inflammation Lung Lung diseases Lungs Mast cells Meta-analysis Monocytes Obstructive lung disease Pathogenesis Pulmonary Disease, Chronic Obstructive - genetics Respiratory diseases Ribonucleic acid Risk Factors RNA Transcriptome - genetics Transcriptomics
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