A cell-based assay to discover inhibitors of Zika virus RNA-dependent RNA polymerase

Zika virus (ZIKV) belongs to Flaviviridae, the Flavivirus genus. Its infection causes congenital brain abnormalities and Guillain-Barré syndrome. However, there are no effective vaccines, no FDA-approved drugs to manage ZIKV infection. The non-structural protein NS5 of ZIKV has been recognized as a...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2024-01, Vol.589, p.109939-109939, Article 109939
Hauptverfasser:	Wang, Lidan, Zhou, Rui, Liu, Yitong, Guo, Saisai, Yi, Dongrong, Zhao, Jianyuan, Li, Quanjie, Zhang, Yongxin, Liang, Chen, Wang, Jing, Shan, Guangzhi, Cen, Shan
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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