Disease activity is associated with changes in the innate immune function in patients with systemic lupus erythematosus

Objective To address the relationship between systemic lupus erythematosus (SLE) disease activity and the functional parameters of the innate immunity. Methods We evaluated a cohort of 26 adult SLE patients and 10 sex and age-paired healthy donors. When the patients had a disease flare (baseline) an...

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Veröffentlicht in:	Clinical rheumatology 2024, Vol.43 (1), p.501-509
Hauptverfasser:	Torres-Ruiz, Jiram, Rull-Gabayet, Marina, Mejía-Domínguez, Nancy R., Carrillo-Vázquez, Daniel Alberto, Reyes-Islas, Juan Alberto, Cassiano-Quezada, Fabiola, Cuellar-Rodríguez, Jennifer, Sierra-Madero, Juan, Sánchez, Jessica Márquez, Serrano-García, Jesús Salvador, González, Alexia Esquinca, Juárez-Vega, Guillermo, Tapia-Rodríguez, Miguel, Gómez-Martín, Diana
Format:	Artikel
Sprache:	eng
Schlagworte:	adults antibiotics cohort studies Confocal microscopy disease prevention Escherichia coli Flow cytometry Immune response Immunosuppressive agents Innate immunity Leukocytes (neutrophilic) linear models Lipopolysaccharides Lupus lupus erythematosus Medicine Medicine & Public Health Monocytes Neutrophils Original Article Phagocytes Phagocytosis Prednisone Prophylaxis Respiratory burst Rheumatology Systemic lupus erythematosus TLR2 protein Toll-like receptors
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