Osthole inhibits GSK-3β/AMPK/mTOR pathway-controlled glycolysis and increases radiosensitivity of subcutaneous transplanted hepatocellular carcinoma in nude mice

Purpose Osthole possesses anti-tumor activities. However, whether osthole can have a radiosensitization effect on hepatic cancer remains unclear. Here, an HCC-LM3 cells-inoculated subcutaneous transplanted tumor was adopted to explore the effect of osthole. Methods The tumor-bearing mice were treate...

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Veröffentlicht in:Strahlentherapie und Onkologie 2024-05, Vol.200 (5), p.444-452
Hauptverfasser: Huang, Hui, Xue, Jie, Xie, Mei-Lin, Xie, Tao
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Sprache:eng
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