Inducing in situ M2 macrophage polarization to promote the repair of bone defects via scaffold-mediated sustained delivery of luteolin

Immunoregulation mediated bone tissue engineering (BTE) has demonstrated huge potential in promoting repair of critical-size bone defects (CSBDs). The trade-off between stable immunoregulation function and extended immunoregulation period has posed a great challenge to this strategy. Here, we report...

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Veröffentlicht in:Journal of controlled release 2024-01, Vol.365, p.889-904
Hauptverfasser: Hu, Yan, Tang, Lixi, Wang, Zheng, Yan, Honghan, Yi, Xinzeyu, Wang, Huimin, Ma, Liya, Yang, Changying, Ran, Jiabing, Yu, Aixi
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Sprache:eng
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