The MAGIC trial: a pragmatic, multicentre, parallel, noninferiority, randomised trial of melatonin versus midazolam in the premedication of anxious children attending for elective surgery under general anaesthesia

Child anxiety before general anaesthesia and surgery is common. Midazolam is a commonly used premedication to address this. Melatonin is an alternative anxiolytic, however trials evaluating its efficacy in children have delivered conflicting results. This multicentre, double-blind randomised trial w...

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Veröffentlicht in:British journal of anaesthesia : BJA 2024-01, Vol.132 (1), p.76-85
Hauptverfasser: Bolt, Robert, Hyslop, Marie C, Herbert, Esther, Papaioannou, Diana E, Totton, Nikki, Wilson, Matthew J, Clarkson, Janet, Evans, Christopher, Ireland, Nicholas, Kettle, Jennifer, Marshman, Zoe, Norrington, Amy C, Paton, Robert H, Vernazza, Christopher, Deery, Christopher
Format: Artikel
Sprache:eng
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