Deficiency of inflammation-sensing protein neuropilin-2 in myeloid-derived macrophages exacerbates colitis via NF-κB activation

Neuropilin-2 (NRP2) is a multifunctional protein engaged in the regulation of angiogenesis, lymphangiogenesis, axon guidance, and tumor metastasis, but its function in colitis remains unclear. Here, we found that NRP2 was an inflammation-sensing protein rapidly and dramatically induced in myeloid ce...

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Veröffentlicht in:The Journal of pathology 2024-02, Vol.262 (2), p.175-188
Hauptverfasser: Li, Tong, Ran, Jingjing, Miao, Zhiyong, Yang, Min, Mou, Dachao, Jiang, Yunhan, Xu, Xiaoqiu, Xie, Qibing, Jin, Ke
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Sprache:eng
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