WAVE3 Facilitates the Tumorigenesis and Metastasis of Tongue Squamous Cell Carcinoma via EMT

Wiskott-Aldrich syndrome protein family verprolin-homologous domain-containing protein 3 (WAVE3) is reported as an oncogene regulating cell proliferation and motility in multiple malignancies, while its role in tongue squamous cell carcinoma (TSCC) remains unknown. This study aimed to explore the ex...

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Veröffentlicht in:	Applied biochemistry and biotechnology 2024-07, Vol.196 (7), p.4287-4302
Hauptverfasser:	Wang, Wei, Zhang, Chenwei, Xiong, Meihua, Jiang, Lin, Fang, Zhiyi, Zhou, Hanjian, Shao, Yisen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biochemistry Biotechnology carcinogenesis Carcinogenesis - genetics Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Cell growth Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Chemistry Chemistry and Materials Science Cholecystokinin Cytoplasm death Epithelial-Mesenchymal Transition Expression vectors family Female Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Male Malignancy Metastases Metastasis Middle Aged Neoplasm Metastasis oncogenes Original Article patients Polymerase chain reaction Protein expression protein synthesis Proteins quantitative polymerase chain reaction Real time risk Risk analysis Squamous cell carcinoma therapeutics Tongue Tongue Neoplasms - genetics Tongue Neoplasms - metabolism Tongue Neoplasms - pathology Tumor cells Tumorigenesis viability Western blotting Wiskott-Aldrich syndrome Wiskott-Aldrich Syndrome Protein Family - genetics Wiskott-Aldrich Syndrome Protein Family - metabolism
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