Alpha-7 Nicotinic Acetylcholine Receptor Activation Inhibits Trauma Induced Pronociceptive Autoimmune Responses

Both autonomic nervous system dysfunction and immune system activation are characteristic of chronic pain after limb injuries. Cholinergic agonists reduce immune system activation in many settings. We hypothesized, therefore, that alpha-7 nicotinic acetylcholine receptor (α7nAChR) agonist administra...

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Veröffentlicht in:	The journal of pain 2024-05, Vol.25 (5), p.104422-104422, Article 104422
Hauptverfasser:	Li, Wen-wu, Shi, Xiao-you, Wei, Tzuping, Guo, Tian-Zhi, Kingery, Wade S., Clark, John David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive immunity Autonomic nervous system Cytokine Fracture Nicotinic acetylcholine receptor Pain
Online-Zugang:	Volltext
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