The elusive nature of the oligoclonal bands in multiple sclerosis

Intrathecal immunoglobulin G (IgG) and oligoclonal bands (OCBs) detected in both the brain and cerebrospinal fluid (CSF) are seminal features of multiple sclerosis (MS). The presence of OCBs correlates with elevated disease burden and severity and supports the diagnosis of MS. Despite numerous inves...

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Veröffentlicht in:	Journal of neurology 2024, Vol.271 (1), p.116-124
Hauptverfasser:	Kennedy, Peter G. E., George, Woro, Yu, Xiaoli
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigen-antibody complexes Brain injury Cerebrospinal fluid Demyelination Diagnosis Disease Epstein-Barr virus Epstein-Barr Virus Infections Genetic control Herpesvirus 4, Human Humans Immunoglobulin G Immunoglobulin G - cerebrospinal fluid Lymphocytes B Medicine Medicine & Public Health Multiple Sclerosis Neurology Neuroradiology Neurosciences Oligoclonal Bands - cerebrospinal fluid Pathogenesis Review
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