Bradykinin produced during Plasmodium falciparum erythrocytic cycle drives monocyte adhesion to human brain microvascular endothelial cells

[Display omitted] •P. falciparum conditioned medium increased monocytes adhesion to brain endothelium.•P. falciparum conditioned medium effect is mediated by B1R and B2R activation.•P. falciparum-derived bradykinin increased ICAM-1 expression on monocytes surface. Cerebral malaria (CM) pathogenesis...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2024-01, Vol.1822, p.148669-148669, Article 148669
Hauptverfasser:	Alves, Sarah A.S., Teixeira, Douglas E., Peruchetti, Diogo B., Silva, Leandro S., Brandão, Luiz Felipe P., Caruso-Neves, Celso, Pinheiro, Ana Acacia S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood brain barrier Blood-Brain Barrier - physiopathology Bradykinin Bradykinin - metabolism Cell Adhesion - physiology Cerebral malaria Culture Media, Conditioned - pharmacology Endothelial Cells - drug effects Endothelial Cells - physiology Erythrocytes - parasitology Humans ICAM-1 expression Inflammatory response Kallikrein kinin system Malaria, Cerebral - metabolism Malaria, Cerebral - parasitology Malaria, Falciparum - metabolism Malaria, Falciparum - parasitology Monocytes - physiology Plasmodium falciparum Plasmodium falciparum - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!