Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL + -Staphylococcus aureus infections

Staphylococcus aureus strains that produce the toxin Panton-Valentine leukocidin (PVL-SA) frequently cause recurrent skin and soft tissue infections. PVL binds to and kills human neutrophils, resulting in the formation of neutrophil extracellular traps (NETs), but the pathomechanism has not been ext...

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Veröffentlicht in:	Journal of leukocyte biology 2024-01, Vol.115 (2), p.222-234
Hauptverfasser:	Jhelum, Hina, Čerina, Dora, Harbort, C J, Lindner, Andreas, Hanitsch, Leif Gunnar, Leistner, Rasmus, Schröder, Jennyver-Tabea, von Bernuth, Horst, Stegemann, Miriam Songa, Schürmann, Mariana, Zychlinsky, Arturo, Krüger, Renate, Marsman, Gerben
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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