Pan-cancer scRNA-seq analysis reveals immunological and diagnostic significance of the peripheral blood mononuclear cells

Abstract Peripheral blood mononuclear cells (PBMCs) reflect systemic immune response during cancer progression. However, a comprehensive understanding of the composition and function of PBMCs in cancer patients is lacking, and the potential of these features to assist cancer diagnosis is also unclea...

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Veröffentlicht in:	Human molecular genetics 2024-02, Vol.33 (4), p.342-354
Hauptverfasser:	Zhang, Yuanhang, Zhou, Xiaorui, Zhong, Yu, Chen, Xi, Li, Zeyu, Li, Rui, Qin, Pengfei, Wang, Shanshan, Yin, Jianhua, Liu, Shang, Jiang, Miaomiao, Yu, Qichao, Hou, Yong, Liu, Shiping, Wu, Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation Cell Transformation, Neoplastic Humans Leukocytes, Mononuclear Neoplasms - diagnosis Neoplasms - genetics Single-Cell Gene Expression Analysis
Online-Zugang:	Volltext
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