Secretory phospholipase (sPLA2-IIA) regulates breast cancer stem cells differentiation and metastatic potential

Breast cancer is the second most cancer worldwide in females. The primary factor responsible for tumor recurrence is the presence of breast cancer stem cells (BCSCs), which escape the chemo-radiotherapy. In this study, we have investigated the role of Secretory phospholipase-A2 Group 2A (sPLA2-IIA)...

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Veröffentlicht in:	Biochemical and biophysical research communications 2023-10, Vol.677, p.98-104
Hauptverfasser:	Mehta, Darshan, Shaikh, Sana, Mohanty, Bhabani, Chaudhari, Pradip, Waghmare, Sanjeev K.
Format:	Artikel
Sprache:	eng
Schlagworte:	BCSCs BCSCs differentiation breast neoplasms EGFR signaling Epithelial to mesenchymal transition (EMT) metastasis neoplasm cells phospholipase A2 phospholipases sPLA2-IIA Tumorigenic potential
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