Novel customized age-dependent corneal membranes and interactions with biodegradable nanoparticles loaded with dexibuprofen

Ocular inflammation is one of the most prevalent diseases in ophthalmology and it is currently treated using eye drops of nonsteroidal antiinflammatory drugs such as dexibuprofen (DXI). However, their bioavailability is low and therefore, PLGA nanoparticles constitute a suitable approach to be admin...

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Veröffentlicht in:	Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2023-08, Vol.228, p.113394-113394, Article 113394
Hauptverfasser:	Esteruelas, Gerard, Ortiz, Alba, Prat, Josefina, Vega, Estefania, Muñoz-Juncosa, Montserrat, López, Maria Luisa Garcia, Ettcheto, Miren, Camins, Antoni, Sánchez-López, Elena, Pujol, Montserrat
Format:	Artikel
Sprache:	eng
Schlagworte:	adhesion adults Animals anisotropy bioavailability biodegradability Biodegradable nanoparticles confocal microscopy Cornea Corneal membrane models Dexibuprofen Ibuprofen - pharmacology inflammation Langmuir monolayers Lipids Liposomes Mice Nanoparticles ophthalmology
Online-Zugang:	Volltext
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