Combination treatment of bortezomib and epirubicin increases the expression of TNFRSF10 A/B, and induces TRAIL-mediated cell death in colorectal cancer cells

Colorectal cancer is one of the most common cancers worldwide, affecting the colon and rectum. A major problem in the treatment of colorectal cancer is acquired chemoresistance, including resistance against death receptor-induced apoptosis. Therefore, investigating new biomarkers for the treatment o...

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Veröffentlicht in:	Biochemical and biophysical research communications 2023-10, Vol.675, p.33-40
Hauptverfasser:	Caldiran, Feyzanur, Berkel, Caglar, Yilmaz, Esra, Kucuk, Burak, Cacan, Aslihan Hatun, Citli, Senol, Canpolat, Emel, Cacan, Ercan
Format:	Artikel
Sprache:	eng
Schlagworte:	apoptosis bioinformatics biomarkers Bortezomib caspase-3 colon Colorectal cancer colorectal neoplasms death death domain receptors Epirubicin ligands neutrophils rectum TNFRSF10A TNFRSF10B TRAIL-DR
Online-Zugang:	Volltext
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