Crystalline Light Chain Casts and Hypercalcemia Induced Acute Kidney Injury: A Rare Presentation of Multiple Myeloma

The most common cause of acute kidney injury (AKI) in multiple myeloma is light-chain cast nephropathy (LCCN), which consists of a light chain and Tamm-Horsfall protein (THP). We herein report a 46-year-old woman with hypercalcemia and AKI. A renal biopsy showed crystalline casts, which were consist...

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Veröffentlicht in:	Internal Medicine 2024/06/15, Vol.63(12), pp.1751-1755
Hauptverfasser:	Nishigaito, Toshiya, Mitsumoto, Kensuke, Katsunuma, Rinko, Hirai, Yuri, Yamashita, Chikako, Mizumoto, Aya, Uzu, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - diagnosis Acute Kidney Injury - etiology Biopsy Bortezomib Bortezomib - therapeutic use Calcium (blood) cast nephropathy crystalline cast Crystallization Female Humans Hypercalcemia Hypercalcemia - blood Hypercalcemia - diagnosis Hypercalcemia - etiology Immunoglobulin Light Chains - blood Kidneys Light chains Middle Aged Multiple myeloma Multiple Myeloma - complications Multiple Myeloma - diagnosis Nephropathy Tamm-Horsfall protein
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