Growth differentiation factor-15 stimulates the synthesis of corticotropin-releasing factor in hypothalamic 4B cells

Growth differentiation factor-15 (GDF15) is a stress-activated cytokine that regulates cell growth and inflammatory and stress responses. We previously reported the role and regulation of GDF15 in pituitary corticotrophs. Dexamethasone increases Gdf15 gene expression levels and production. GDF15 sup...

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Veröffentlicht in:	Peptides (New York, N.Y. : 1980) N.Y. : 1980), 2023-12, Vol.170, p.171112-171112, Article 171112
Hauptverfasser:	Tasso, Mizuki, Kageyama, Kazunori, Iwasaki, Yasumasa, Watanuki, Yutaka, Niioka, Kanako, Takayasu, Shinobu, Daimon, Makoto
Format:	Artikel
Sprache:	eng
Schlagworte:	cAMP-dependent protein kinase cell growth corticotropin corticotropin-releasing hormone Corticotropin-Releasing Hormone - genetics Corticotropin-Releasing Hormone - metabolism cytokines dexamethasone family gene expression glucocorticoids Growth Differentiation Factors - genetics Growth Differentiation Factors - metabolism Growth Differentiation Factors - pharmacology Hypothalamus - metabolism luciferase phosphorylation Promoter Regions, Genetic quantitative polymerase chain reaction Receptors, Corticotropin-Releasing Hormone - genetics Receptors, Corticotropin-Releasing Hormone - metabolism RNA, Messenger - metabolism
Online-Zugang:	Volltext
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