β-Caryophyllene decreases neuroinflammation and exerts neuroprotection of dopaminergic neurons in a model of hemiparkinsonism through inhibition of the NLRP3 inflammasome

Parkinson's disease represents a neurodegenerative condition characterized by the progressive loss of dopaminergic neurons within the Substantia Nigra pars compacta (SNpc), resulting in diminished dopamine levels in the striatum (STR) and chronic neuroinflammation. Recent investigations have pr...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Parkinsonism & related disorders 2023-12, Vol.117, p.105906-105906, Article 105906
Hauptverfasser:	Brand-Rubalcava, Patricia Alejandra, Tejeda-Martínez, Aldo Rafael, González-Reynoso, Orfil, Nápoles-Medina, Angelica Yanet, Chaparro-Huerta, Verónica, Flores-Soto, Mario Eduardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caspases - metabolism Caspases - pharmacology Disease Models, Animal Dopaminergic Neurons - metabolism Humans Inflammasomes - metabolism Inflammasomes - pharmacology Mice Mice, Inbred C57BL Neuroinflammatory Diseases Neuroprotection Neuroprotective Agents - pharmacology NLR Family, Pyrin Domain-Containing 3 Protein Oxidopamine Parkinson Disease - drug therapy Parkinson Disease - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!