A novel PSMA targeted dual-function near-infrared fluorescence and PET probe for the image-guided surgery and detection of prostate cancer

Purpose Prostate-specific membrane antigen (PSMA) is a promising diagnostic biomarker for prostate cancer (PCa). NYM016, a novel small-molecule PSMA-targeted fluorescence probe for the surgical navigation of PCa, was designed in this work. Furthermore, the potential of the PET agent [ 68 Ga]Ga–NYM01...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of nuclear medicine and molecular imaging 2024-08, Vol.51 (10), p.2998-3008
Hauptverfasser:	Fu, Haitian, Lou, Kequan, He, Huihui, Wang, Yanjuan, Mi, Yuanyuan, Li, Wenjin, Chen, Liping, Zhang, Yu, Yu, Chunjing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adverse events Aged Animal models Animals Antigens, Surface - metabolism Biomarkers Cardiology Cell Line, Tumor Chelation Fluorescence Fluorescent Dyes - chemistry Fluorescent indicators Gallium isotopes Gallium Radioisotopes Glutamate Carboxypeptidase II - metabolism Humans I.R. radiation Imaging Infrared imagery Lesions Male Medical imaging Medicine Medicine & Public Health Metastases Mice Navigation Nuclear Medicine Oncology Original Article Orthopedics Patients Positron emission Positron-Emission Tomography - methods Prostate cancer Prostatic Neoplasms - diagnostic imaging Prostatic Neoplasms - surgery Prostatitis Radioactive tracers Radioisotopes Radiology Surgery, Computer-Assisted - methods Surgical instruments Tissue Distribution Xenografts Xenotransplantation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!