Novel quinoxaline-3-propanamides as VGFR-2 inhibitors and apoptosis inducers

Vascular endothelial growth factor receptor-2 is a vital target for therapeutic mediation in various types of cancer. This study was aimed at exploring the cytotoxic activity of seventeen novel quinoxaline-3-propanamides against colon cancer (HCT-116) and breast cancer (MCF-7) using MTT assay. Resul...

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Veröffentlicht in:	RSC advances 2023-10, Vol.13 (45), p.3198-31924
Hauptverfasser:	Ismail, Magda M. F, Shawer, Taghreed Z, Ibrahim, Rabab S, Abusaif, Mostafa S, Kamal, Mona M, Allam, Rasha M, Ammar, Yousry A
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Apoptosis Cancer Cell death Chemistry Doxorubicin Efflux Flow cytometry Growth factors Proteins Quinoxalines Receptors Substrates Vascular endothelial growth factor
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