Satisfactory patient-reported outcomes in patients treated with impaction bone grafting and autologous matrix-induced chondrogenesis for osteochondral knee defects
Purpose Osteochondral knee defects usually affect young, active patients and may alter knee biomechanics and progressively lead to joint degeneration. Various treatment options exist with autologous, impaction bone grafting in combination with autologous matrix-induced chondrogenesis (BG-AMIC) being...
Gespeichert in:
| Veröffentlicht in: | Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA sports traumatology, arthroscopy : official journal of the ESSKA, 2023-12, Vol.31 (12), p.5698-5706 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 5706 |
|---|---|
| container_issue | 12 |
| container_start_page | 5698 |
| container_title | Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA |
| container_volume | 31 |
| creator | Mitrousias, Vasileios Chalatsis, Georgios Mylonas, Theodoros Siouras, Athanasios Stergiadou, Stella Panteliadou, Freideriki Vlychou, Marianna Hantes, Michael |
| description | Purpose
Osteochondral knee defects usually affect young, active patients and may alter knee biomechanics and progressively lead to joint degeneration. Various treatment options exist with autologous, impaction bone grafting in combination with autologous matrix-induced chondrogenesis (BG-AMIC) being a less-expensive, one-step, promising option. The purpose of this study is to evaluate the clinical and radiological mid-term outcomes of large osteochondral lesions treated with BG-AMIC, identify a possible correlation between the two and report postoperative complications and reoperation rate.
Methods
A retrospective analysis of 25 patients treated with the BG-AMIC technique for knee osteochondral lesions was performed. Patients were assessed using the following PROMs: the IKDC, the KOOS and the Lysholm score, the Tegner activity scale and a patient acceptable symptom state (PASS). The EQ-5D-5L score was used to assess health-related quality of life. Radiological assessment was performed using the MOCART 2.0 score on a 3 T MRI.
Results
At a mean of 3.8 (± 0.8)-year follow-up, all functional scores increased significantly (
p
|
| doi_str_mv | 10.1007/s00167-023-07626-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2884675646</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2901289276</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4260-d4db17f728b1877fc4292acc52f8798cf66f834a5ca4877c330973b223676c333</originalsourceid><addsrcrecordid>eNqNkcFuFSEUhonR2Gv1BVwYEjduUAa4MOOuNlaNTVxU14RhDlPqDFyBSb3P0xct12k1cWFcwTnn__4c-BF63tDXDaXqTaa0kYpQxglVkknCHqBNIzgnigv1EG1oJxhhdCuP0JOcryitV9E9RkdcdVRQ2W7QzYUpPjtjS0x7vKsFhEIS7GIqMOC4FBtnyNiH-2HGJYE5DK99ucR-3lXYx4D7GACPybjiw4hNGLBZSpziGJeMZ1OS_0l8GBZbUXsZw5DiCAGyz9jFhGMuENe-mfD3AIAHcGBLfooeOTNleHZ3HqNvZ--_nn4k518-fDo9OSdWMEnJIIa-UU6xtm9apVztdsxYu2WuVV1rnZSu5cJsrRF1bjmnneI9Y1wqWSt-jF6tvrsUfyyQi559tjBNJkB9g2ZtK6SqXyir9OVf0qu4pFC306yjDWs7pg4qtqpsijkncHqX_GzSXjdUHyLUa4S6Rqh_RahZhV7cWS_9DMNv5D6zKni7Cq79BPv_sNSfL07endFWcVphvsK5cmGE9Gfxf-x0C0YLu5w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2901289276</pqid></control><display><type>article</type><title>Satisfactory patient-reported outcomes in patients treated with impaction bone grafting and autologous matrix-induced chondrogenesis for osteochondral knee defects</title><source>SpringerNature Journals</source><source>Access via Wiley Online Library</source><creator>Mitrousias, Vasileios ; Chalatsis, Georgios ; Mylonas, Theodoros ; Siouras, Athanasios ; Stergiadou, Stella ; Panteliadou, Freideriki ; Vlychou, Marianna ; Hantes, Michael</creator><creatorcontrib>Mitrousias, Vasileios ; Chalatsis, Georgios ; Mylonas, Theodoros ; Siouras, Athanasios ; Stergiadou, Stella ; Panteliadou, Freideriki ; Vlychou, Marianna ; Hantes, Michael</creatorcontrib><description>Purpose
Osteochondral knee defects usually affect young, active patients and may alter knee biomechanics and progressively lead to joint degeneration. Various treatment options exist with autologous, impaction bone grafting in combination with autologous matrix-induced chondrogenesis (BG-AMIC) being a less-expensive, one-step, promising option. The purpose of this study is to evaluate the clinical and radiological mid-term outcomes of large osteochondral lesions treated with BG-AMIC, identify a possible correlation between the two and report postoperative complications and reoperation rate.
Methods
A retrospective analysis of 25 patients treated with the BG-AMIC technique for knee osteochondral lesions was performed. Patients were assessed using the following PROMs: the IKDC, the KOOS and the Lysholm score, the Tegner activity scale and a patient acceptable symptom state (PASS). The EQ-5D-5L score was used to assess health-related quality of life. Radiological assessment was performed using the MOCART 2.0 score on a 3 T MRI.
Results
At a mean of 3.8 (± 0.8)-year follow-up, all functional scores increased significantly (
p
< 0.005) when compared to the preoperative baseline. IKDC increased from 44.5 (± 15.9) to 81.4 (± 14.7), KOOS from 41.5 (± 16.1) to 91.6 (± 11.6) and Lysholm from 54.4 (± 23) to 95.2 (± 5.5) (
p
< 0.005). The EQ-5D-5L score also revealed a significant improvement [59.9 (± 25) to 93.4 (± 10.2),
p
< 0.005]. Mean Tegner score reached pre-injury levels. The PASS was positive in 100% of patients. The minimum clinically important difference was reached in all PROMs except for the KOOS Sports subscale. There were no re-operations. Morphological evaluation of the repair tissue using the MOCART 2.0 score revealed a mean total score of 52.8 (± 30.5). A statistically significant, positive correlation was found between the MOCART 2.0 score and the IKDC score, the KOOS ADL subscale and the EQ-5D-5L (
p
< 0.05).
Conclusion
BG-AMIC is a safe and reliable option for treating deep, knee osteochondral lesions, providing a statistically significant and clinically important improvement in patient-reported outcomes. No complications were noticed, and no re-operations were performed after the procedure. A moderate positive correlation between the MOCART 2.0 score and the IKDC, KOOS ADL and EQ-5D-5L was noticed. However, this correlation is not necessarily clinically relevant, and excellent clinical results can be expected even in patients with low MOCART scores.
Level of evidence
III.</description><identifier>ISSN: 0942-2056</identifier><identifier>EISSN: 1433-7347</identifier><identifier>DOI: 10.1007/s00167-023-07626-2</identifier><identifier>PMID: 37904068</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Autografts ; Autologous matrix‐induced chondrogenesis ; Biomechanics ; Bone grafts ; Bone matrix ; Bone surgery ; Chondrogenesis ; Clinical outcomes ; Complications ; Correlation ; Defects ; Degeneration ; Grafting ; Grafts ; Impaction bone grafting ; Knee ; Lesions ; Medicine ; Medicine & Public Health ; MOCART 2.0 score ; Orthopedics ; Osteochondral defects ; Patients ; Postoperative ; Quality assessment ; Quality of life ; Skin & tissue grafts ; Sports Medicine ; Statistical analysis ; Substitute bone</subject><ispartof>Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023-12, Vol.31 (12), p.5698-5706</ispartof><rights>The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023 European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA)</rights><rights>2023. The Author(s) under exclusive licence to European Society of Sports Traumatology, Knee Surgery, Arthroscopy (ESSKA).</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4260-d4db17f728b1877fc4292acc52f8798cf66f834a5ca4877c330973b223676c333</citedby><cites>FETCH-LOGICAL-c4260-d4db17f728b1877fc4292acc52f8798cf66f834a5ca4877c330973b223676c333</cites><orcidid>0000-0001-9494-6048</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00167-023-07626-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00167-023-07626-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,41488,42557,45574,45575,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37904068$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mitrousias, Vasileios</creatorcontrib><creatorcontrib>Chalatsis, Georgios</creatorcontrib><creatorcontrib>Mylonas, Theodoros</creatorcontrib><creatorcontrib>Siouras, Athanasios</creatorcontrib><creatorcontrib>Stergiadou, Stella</creatorcontrib><creatorcontrib>Panteliadou, Freideriki</creatorcontrib><creatorcontrib>Vlychou, Marianna</creatorcontrib><creatorcontrib>Hantes, Michael</creatorcontrib><title>Satisfactory patient-reported outcomes in patients treated with impaction bone grafting and autologous matrix-induced chondrogenesis for osteochondral knee defects</title><title>Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA</title><addtitle>Knee Surg Sports Traumatol Arthrosc</addtitle><addtitle>Knee Surg Sports Traumatol Arthrosc</addtitle><description>Purpose
Osteochondral knee defects usually affect young, active patients and may alter knee biomechanics and progressively lead to joint degeneration. Various treatment options exist with autologous, impaction bone grafting in combination with autologous matrix-induced chondrogenesis (BG-AMIC) being a less-expensive, one-step, promising option. The purpose of this study is to evaluate the clinical and radiological mid-term outcomes of large osteochondral lesions treated with BG-AMIC, identify a possible correlation between the two and report postoperative complications and reoperation rate.
Methods
A retrospective analysis of 25 patients treated with the BG-AMIC technique for knee osteochondral lesions was performed. Patients were assessed using the following PROMs: the IKDC, the KOOS and the Lysholm score, the Tegner activity scale and a patient acceptable symptom state (PASS). The EQ-5D-5L score was used to assess health-related quality of life. Radiological assessment was performed using the MOCART 2.0 score on a 3 T MRI.
Results
At a mean of 3.8 (± 0.8)-year follow-up, all functional scores increased significantly (
p
< 0.005) when compared to the preoperative baseline. IKDC increased from 44.5 (± 15.9) to 81.4 (± 14.7), KOOS from 41.5 (± 16.1) to 91.6 (± 11.6) and Lysholm from 54.4 (± 23) to 95.2 (± 5.5) (
p
< 0.005). The EQ-5D-5L score also revealed a significant improvement [59.9 (± 25) to 93.4 (± 10.2),
p
< 0.005]. Mean Tegner score reached pre-injury levels. The PASS was positive in 100% of patients. The minimum clinically important difference was reached in all PROMs except for the KOOS Sports subscale. There were no re-operations. Morphological evaluation of the repair tissue using the MOCART 2.0 score revealed a mean total score of 52.8 (± 30.5). A statistically significant, positive correlation was found between the MOCART 2.0 score and the IKDC score, the KOOS ADL subscale and the EQ-5D-5L (
p
< 0.05).
Conclusion
BG-AMIC is a safe and reliable option for treating deep, knee osteochondral lesions, providing a statistically significant and clinically important improvement in patient-reported outcomes. No complications were noticed, and no re-operations were performed after the procedure. A moderate positive correlation between the MOCART 2.0 score and the IKDC, KOOS ADL and EQ-5D-5L was noticed. However, this correlation is not necessarily clinically relevant, and excellent clinical results can be expected even in patients with low MOCART scores.
Level of evidence
III.</description><subject>Autografts</subject><subject>Autologous matrix‐induced chondrogenesis</subject><subject>Biomechanics</subject><subject>Bone grafts</subject><subject>Bone matrix</subject><subject>Bone surgery</subject><subject>Chondrogenesis</subject><subject>Clinical outcomes</subject><subject>Complications</subject><subject>Correlation</subject><subject>Defects</subject><subject>Degeneration</subject><subject>Grafting</subject><subject>Grafts</subject><subject>Impaction bone grafting</subject><subject>Knee</subject><subject>Lesions</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>MOCART 2.0 score</subject><subject>Orthopedics</subject><subject>Osteochondral defects</subject><subject>Patients</subject><subject>Postoperative</subject><subject>Quality assessment</subject><subject>Quality of life</subject><subject>Skin & tissue grafts</subject><subject>Sports Medicine</subject><subject>Statistical analysis</subject><subject>Substitute bone</subject><issn>0942-2056</issn><issn>1433-7347</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkcFuFSEUhonR2Gv1BVwYEjduUAa4MOOuNlaNTVxU14RhDlPqDFyBSb3P0xct12k1cWFcwTnn__4c-BF63tDXDaXqTaa0kYpQxglVkknCHqBNIzgnigv1EG1oJxhhdCuP0JOcryitV9E9RkdcdVRQ2W7QzYUpPjtjS0x7vKsFhEIS7GIqMOC4FBtnyNiH-2HGJYE5DK99ucR-3lXYx4D7GACPybjiw4hNGLBZSpziGJeMZ1OS_0l8GBZbUXsZw5DiCAGyz9jFhGMuENe-mfD3AIAHcGBLfooeOTNleHZ3HqNvZ--_nn4k518-fDo9OSdWMEnJIIa-UU6xtm9apVztdsxYu2WuVV1rnZSu5cJsrRF1bjmnneI9Y1wqWSt-jF6tvrsUfyyQi559tjBNJkB9g2ZtK6SqXyir9OVf0qu4pFC306yjDWs7pg4qtqpsijkncHqX_GzSXjdUHyLUa4S6Rqh_RahZhV7cWS_9DMNv5D6zKni7Cq79BPv_sNSfL07endFWcVphvsK5cmGE9Gfxf-x0C0YLu5w</recordid><startdate>202312</startdate><enddate>202312</enddate><creator>Mitrousias, Vasileios</creator><creator>Chalatsis, Georgios</creator><creator>Mylonas, Theodoros</creator><creator>Siouras, Athanasios</creator><creator>Stergiadou, Stella</creator><creator>Panteliadou, Freideriki</creator><creator>Vlychou, Marianna</creator><creator>Hantes, Michael</creator><general>Springer Berlin Heidelberg</general><general>Springer‐Verlag</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9494-6048</orcidid></search><sort><creationdate>202312</creationdate><title>Satisfactory patient-reported outcomes in patients treated with impaction bone grafting and autologous matrix-induced chondrogenesis for osteochondral knee defects</title><author>Mitrousias, Vasileios ; Chalatsis, Georgios ; Mylonas, Theodoros ; Siouras, Athanasios ; Stergiadou, Stella ; Panteliadou, Freideriki ; Vlychou, Marianna ; Hantes, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4260-d4db17f728b1877fc4292acc52f8798cf66f834a5ca4877c330973b223676c333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Autografts</topic><topic>Autologous matrix‐induced chondrogenesis</topic><topic>Biomechanics</topic><topic>Bone grafts</topic><topic>Bone matrix</topic><topic>Bone surgery</topic><topic>Chondrogenesis</topic><topic>Clinical outcomes</topic><topic>Complications</topic><topic>Correlation</topic><topic>Defects</topic><topic>Degeneration</topic><topic>Grafting</topic><topic>Grafts</topic><topic>Impaction bone grafting</topic><topic>Knee</topic><topic>Lesions</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>MOCART 2.0 score</topic><topic>Orthopedics</topic><topic>Osteochondral defects</topic><topic>Patients</topic><topic>Postoperative</topic><topic>Quality assessment</topic><topic>Quality of life</topic><topic>Skin & tissue grafts</topic><topic>Sports Medicine</topic><topic>Statistical analysis</topic><topic>Substitute bone</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mitrousias, Vasileios</creatorcontrib><creatorcontrib>Chalatsis, Georgios</creatorcontrib><creatorcontrib>Mylonas, Theodoros</creatorcontrib><creatorcontrib>Siouras, Athanasios</creatorcontrib><creatorcontrib>Stergiadou, Stella</creatorcontrib><creatorcontrib>Panteliadou, Freideriki</creatorcontrib><creatorcontrib>Vlychou, Marianna</creatorcontrib><creatorcontrib>Hantes, Michael</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mitrousias, Vasileios</au><au>Chalatsis, Georgios</au><au>Mylonas, Theodoros</au><au>Siouras, Athanasios</au><au>Stergiadou, Stella</au><au>Panteliadou, Freideriki</au><au>Vlychou, Marianna</au><au>Hantes, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Satisfactory patient-reported outcomes in patients treated with impaction bone grafting and autologous matrix-induced chondrogenesis for osteochondral knee defects</atitle><jtitle>Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA</jtitle><stitle>Knee Surg Sports Traumatol Arthrosc</stitle><addtitle>Knee Surg Sports Traumatol Arthrosc</addtitle><date>2023-12</date><risdate>2023</risdate><volume>31</volume><issue>12</issue><spage>5698</spage><epage>5706</epage><pages>5698-5706</pages><issn>0942-2056</issn><eissn>1433-7347</eissn><abstract>Purpose
Osteochondral knee defects usually affect young, active patients and may alter knee biomechanics and progressively lead to joint degeneration. Various treatment options exist with autologous, impaction bone grafting in combination with autologous matrix-induced chondrogenesis (BG-AMIC) being a less-expensive, one-step, promising option. The purpose of this study is to evaluate the clinical and radiological mid-term outcomes of large osteochondral lesions treated with BG-AMIC, identify a possible correlation between the two and report postoperative complications and reoperation rate.
Methods
A retrospective analysis of 25 patients treated with the BG-AMIC technique for knee osteochondral lesions was performed. Patients were assessed using the following PROMs: the IKDC, the KOOS and the Lysholm score, the Tegner activity scale and a patient acceptable symptom state (PASS). The EQ-5D-5L score was used to assess health-related quality of life. Radiological assessment was performed using the MOCART 2.0 score on a 3 T MRI.
Results
At a mean of 3.8 (± 0.8)-year follow-up, all functional scores increased significantly (
p
< 0.005) when compared to the preoperative baseline. IKDC increased from 44.5 (± 15.9) to 81.4 (± 14.7), KOOS from 41.5 (± 16.1) to 91.6 (± 11.6) and Lysholm from 54.4 (± 23) to 95.2 (± 5.5) (
p
< 0.005). The EQ-5D-5L score also revealed a significant improvement [59.9 (± 25) to 93.4 (± 10.2),
p
< 0.005]. Mean Tegner score reached pre-injury levels. The PASS was positive in 100% of patients. The minimum clinically important difference was reached in all PROMs except for the KOOS Sports subscale. There were no re-operations. Morphological evaluation of the repair tissue using the MOCART 2.0 score revealed a mean total score of 52.8 (± 30.5). A statistically significant, positive correlation was found between the MOCART 2.0 score and the IKDC score, the KOOS ADL subscale and the EQ-5D-5L (
p
< 0.05).
Conclusion
BG-AMIC is a safe and reliable option for treating deep, knee osteochondral lesions, providing a statistically significant and clinically important improvement in patient-reported outcomes. No complications were noticed, and no re-operations were performed after the procedure. A moderate positive correlation between the MOCART 2.0 score and the IKDC, KOOS ADL and EQ-5D-5L was noticed. However, this correlation is not necessarily clinically relevant, and excellent clinical results can be expected even in patients with low MOCART scores.
Level of evidence
III.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>37904068</pmid><doi>10.1007/s00167-023-07626-2</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-9494-6048</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0942-2056 |
| ispartof | Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2023-12, Vol.31 (12), p.5698-5706 |
| issn | 0942-2056 1433-7347 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2884675646 |
| source | SpringerNature Journals; Access via Wiley Online Library |
| subjects | Autografts Autologous matrix‐induced chondrogenesis Biomechanics Bone grafts Bone matrix Bone surgery Chondrogenesis Clinical outcomes Complications Correlation Defects Degeneration Grafting Grafts Impaction bone grafting Knee Lesions Medicine Medicine & Public Health MOCART 2.0 score Orthopedics Osteochondral defects Patients Postoperative Quality assessment Quality of life Skin & tissue grafts Sports Medicine Statistical analysis Substitute bone |
| title | Satisfactory patient-reported outcomes in patients treated with impaction bone grafting and autologous matrix-induced chondrogenesis for osteochondral knee defects |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T22%3A37%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Satisfactory%20patient-reported%20outcomes%20in%20patients%20treated%20with%20impaction%20bone%20grafting%20and%20autologous%20matrix-induced%20chondrogenesis%20for%20osteochondral%20knee%20defects&rft.jtitle=Knee%20surgery,%20sports%20traumatology,%20arthroscopy%20:%20official%20journal%20of%20the%20ESSKA&rft.au=Mitrousias,%20Vasileios&rft.date=2023-12&rft.volume=31&rft.issue=12&rft.spage=5698&rft.epage=5706&rft.pages=5698-5706&rft.issn=0942-2056&rft.eissn=1433-7347&rft_id=info:doi/10.1007/s00167-023-07626-2&rft_dat=%3Cproquest_cross%3E2901289276%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2901289276&rft_id=info:pmid/37904068&rfr_iscdi=true |