Dual action of serotonin on local excitatory and inhibitory neural circuits regulating the corticotropin‐releasing factor neurons in the paraventricular nucleus of the hypothalamus

Serotonergic neurons originating from the raphe nuclei have been proposed to regulate corticotropin‐releasing factor (CRF) neurons in the paraventricular nucleus of the hypothalamus (PVH). Since glutamate‐ and γ‐aminobutyric acid (GABA)‐containing neurons, constituting the hypothalamic local circuit...

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Veröffentlicht in:	Journal of neuroendocrinology 2023-12, Vol.35 (12), p.e13351-n/a
Hauptverfasser:	Sato, Takayuki, Sugaya, Takuma, Talukder, Ashraf Hossain, Tsushima, Yuki, Sasaki, Shotaro, Uchida, Katsuya, Sato, Tatsuya, Ikoma, Yoko, Sakimura, Kenji, Fukuda, Atsuo, Matsui, Ko, Itoi, Keiichi
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxy-2-(di-n-propylamino)tetralin Action potential Agonists Animals Brain slice preparation Corticotropin-Releasing Hormone - metabolism corticotropin‐releasing hormone Excitatory postsynaptic potentials fluorescent protein Glutamatergic transmission Hypothalamus Hypothalamus - metabolism Inhibitory postsynaptic potentials Interneurons knock‐in mouse Mice Neural networks Neurons - metabolism noradrenergic neurons Paraventricular Hypothalamic Nucleus - metabolism Paraventricular nucleus postsynaptic currents Raphe nuclei Serotonin Serotonin - metabolism Synaptic Transmission - physiology Tetrodotoxin Yellow fluorescent protein γ-Aminobutyric acid
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