Alcohol induces hepatocytes necroptosis through the LC3/RIPK1/RIPK3 pathway

Excessive alcohol consumption leads to serious liver injury. Necroptosis is a programmed cell death form, which has been confirmed to be involved in alcoholic liver injury. However, the exact mechanism remains still unclear. In this study, we found that ethanol caused hepatocytes necroptosis by acti...

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Veröffentlicht in:	Food and chemical toxicology 2023-12, Vol.182, p.114124, Article 114124
Hauptverfasser:	Chen, Yuelin, Liu, Meitong, Wei, Hongdi, Guo, Jiakang, Zhang, Shengzhuo, Bu, Xiujuan, Chen, Shanshan, Zhang, Duoduo, Guan, Shuang
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohol Animals Apoptosis Ethanol - toxicity Hepatocytes - metabolism LC3 Liver Liver - metabolism Mice Necroptosis Receptor-Interacting Protein Serine-Threonine Kinases - metabolism RIPK1 RIPK3
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