Bactericidal activity of esculetin is associated with impaired cell wall synthesis by targeting glutamate racemase of Neisseria gonorrhoeae

Neisseria gonorrhoeae (NG), the causative organism of gonorrhea, has been classified by the World Health Organization as ‘Priority’ two organism owing to its increased resistance to antibiotics and even failure of recommended dual therapy with ceftriaxone and azithromycin. As a result, the general a...

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Veröffentlicht in:	Molecular diversity 2024-10, Vol.28 (5), p.3181-3198
Hauptverfasser:	Pawar, Alka, Konwar, Chandrika, Jha, Prakash, Kant, Ravi, Chopra, Madhu, Chaudhry, Uma, Saluja, Daman
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Isomerases - antagonists & inhibitors Amino Acid Isomerases - metabolism Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Biochemistry Biomedical and Life Sciences Biosynthesis Cell Wall - drug effects Cell Wall - metabolism Gonorrhea Life Sciences Microbial Sensitivity Tests Molecular Docking Simulation Neisseria gonorrhoeae - drug effects Neisseria gonorrhoeae - enzymology Organic Chemistry Original Article Peptidoglycan - biosynthesis Peptidoglycan - metabolism Pharmacy Phytochemicals Polymer Sciences Umbelliferones - chemistry Umbelliferones - pharmacology
Online-Zugang:	Volltext
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