Association of Autonomic Symptom Burden with Sudden Sensorineural Hearing Loss
Objective To investigate the autonomic symptom burden in patients with sudden sensorineural hearing loss (SSNHL) and its association with the severity and prognosis. Study Design Observational prospective study. Setting Tertiary academic medical center. Methods Patients diagnosed with SSNHL at a sin...
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| Veröffentlicht in: | Otolaryngology-head and neck surgery 2024-03, Vol.170 (3), p.862-869 |
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| container_title | Otolaryngology-head and neck surgery |
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| creator | Yang, Chao‐Hui Lin, Wei‐Che Chen, Wei‐Chih Luo, Sheng‐Dean Yang, Ming‐Yu Hwang, Chung‐Feng Chen, Shu‐Fang |
| description | Objective
To investigate the autonomic symptom burden in patients with sudden sensorineural hearing loss (SSNHL) and its association with the severity and prognosis.
Study Design
Observational prospective study.
Setting
Tertiary academic medical center.
Methods
Patients diagnosed with SSNHL at a single medical center completed the COMPASS 31 questionnaire, which assesses dysautonomia across 6 domains with 31 questions. A total COMPASS 31 score was calculated by summing the scores from each weighted domain. The treatment outcome was evaluated by the percentage of recovery, calculated as the hearing gain in pure tone average (PTA) after treatment divided by the pretreatment PTA difference between the 2 ears. We defined poor recovery as a percentage of recovery |
| doi_str_mv | 10.1002/ohn.560 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2881713539</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2881713539</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3120-620d72565c0280d5d620c05991dd9c9eb7cc9a0ea226be55f792d3b96269d69e3</originalsourceid><addsrcrecordid>eNp1kEFLwzAYhoMobk7xH0huCtKZpCZpjnOoE8Z2mJ5DmqQu0jYzaRn792ZsevP0vXw8vLw8AFxjNMYIkQe_bseUoRMwxEjwjBWYn4IhwuIxo0IUA3AR4xdCiDHOz8Eg5wXnJKdDsJjE6LVTnfMt9BWc9J1vfeM0XO2aTecb-NQHY1u4dd0arnqzzyvbRh9ca_ugajizKuVPOPcxXoKzStXRXh3vCHy8PL9PZ9l8-fo2ncwznWOCMkaQ4YQyqhEpkKEmPTRKS7ExQgtbcq2FQlYRwkpLacUFMXkpGGHCMGHzEbg79G6C_-5t7GTjorZ1rVrr-yhJkQzgnOYiobcHVIc0MNhKboJrVNhJjORenkzyZJKXyJtjaV821vxxv7YScH8Atq62u_965HK22Nf9AOg4d4o</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2881713539</pqid></control><display><type>article</type><title>Association of Autonomic Symptom Burden with Sudden Sensorineural Hearing Loss</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Yang, Chao‐Hui ; Lin, Wei‐Che ; Chen, Wei‐Chih ; Luo, Sheng‐Dean ; Yang, Ming‐Yu ; Hwang, Chung‐Feng ; Chen, Shu‐Fang</creator><creatorcontrib>Yang, Chao‐Hui ; Lin, Wei‐Che ; Chen, Wei‐Chih ; Luo, Sheng‐Dean ; Yang, Ming‐Yu ; Hwang, Chung‐Feng ; Chen, Shu‐Fang</creatorcontrib><description>Objective
To investigate the autonomic symptom burden in patients with sudden sensorineural hearing loss (SSNHL) and its association with the severity and prognosis.
Study Design
Observational prospective study.
Setting
Tertiary academic medical center.
Methods
Patients diagnosed with SSNHL at a single medical center completed the COMPASS 31 questionnaire, which assesses dysautonomia across 6 domains with 31 questions. A total COMPASS 31 score was calculated by summing the scores from each weighted domain. The treatment outcome was evaluated by the percentage of recovery, calculated as the hearing gain in pure tone average (PTA) after treatment divided by the pretreatment PTA difference between the 2 ears. We defined poor recovery as a percentage of recovery <80%.
Results
A total of 63 SSNHL patients were included. The mean COMPASS 31 score was 23.4 (SD 14). Patients with poor recovery had significantly higher COMPASS 31 scores than those with good recovery (mean 26.4 [SD 14.4] vs 16.9 [SD 10.4]; 95% confidence interval [CI] 2‐17). There was a negative association between COMPASS 31 score and both hearing gain (r = −.323, 95% CI −0.082 to −0.529) and percentage of recovery (r = −.365, 95% CI −0.129 to −0.562). Multivariate analyses of independent factors indicate that patients with higher COMPASS 31 scores had a greater risk for poor recovery (OR 1.06 [95% CI 1.003‐1.117]).
Conclusion
This study highlights the association between autonomic symptom burden and poor hearing outcomes in SSNHL patients. The findings underscore the importance of evaluating autonomic function during the treatment of SSNHL.</description><identifier>ISSN: 0194-5998</identifier><identifier>EISSN: 1097-6817</identifier><identifier>DOI: 10.1002/ohn.560</identifier><identifier>PMID: 37877235</identifier><language>eng</language><publisher>England</publisher><subject>autonomic symptom burden ; COMPASS 31 ; sudden hearing loss</subject><ispartof>Otolaryngology-head and neck surgery, 2024-03, Vol.170 (3), p.862-869</ispartof><rights>2023 American Academy of Otolaryngology–Head and Neck Surgery Foundation.</rights><rights>2023 American Academy of Otolaryngology-Head and Neck Surgery Foundation.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3120-620d72565c0280d5d620c05991dd9c9eb7cc9a0ea226be55f792d3b96269d69e3</cites><orcidid>0000-0003-4055-1686</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fohn.560$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fohn.560$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37877235$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yang, Chao‐Hui</creatorcontrib><creatorcontrib>Lin, Wei‐Che</creatorcontrib><creatorcontrib>Chen, Wei‐Chih</creatorcontrib><creatorcontrib>Luo, Sheng‐Dean</creatorcontrib><creatorcontrib>Yang, Ming‐Yu</creatorcontrib><creatorcontrib>Hwang, Chung‐Feng</creatorcontrib><creatorcontrib>Chen, Shu‐Fang</creatorcontrib><title>Association of Autonomic Symptom Burden with Sudden Sensorineural Hearing Loss</title><title>Otolaryngology-head and neck surgery</title><addtitle>Otolaryngol Head Neck Surg</addtitle><description>Objective
To investigate the autonomic symptom burden in patients with sudden sensorineural hearing loss (SSNHL) and its association with the severity and prognosis.
Study Design
Observational prospective study.
Setting
Tertiary academic medical center.
Methods
Patients diagnosed with SSNHL at a single medical center completed the COMPASS 31 questionnaire, which assesses dysautonomia across 6 domains with 31 questions. A total COMPASS 31 score was calculated by summing the scores from each weighted domain. The treatment outcome was evaluated by the percentage of recovery, calculated as the hearing gain in pure tone average (PTA) after treatment divided by the pretreatment PTA difference between the 2 ears. We defined poor recovery as a percentage of recovery <80%.
Results
A total of 63 SSNHL patients were included. The mean COMPASS 31 score was 23.4 (SD 14). Patients with poor recovery had significantly higher COMPASS 31 scores than those with good recovery (mean 26.4 [SD 14.4] vs 16.9 [SD 10.4]; 95% confidence interval [CI] 2‐17). There was a negative association between COMPASS 31 score and both hearing gain (r = −.323, 95% CI −0.082 to −0.529) and percentage of recovery (r = −.365, 95% CI −0.129 to −0.562). Multivariate analyses of independent factors indicate that patients with higher COMPASS 31 scores had a greater risk for poor recovery (OR 1.06 [95% CI 1.003‐1.117]).
Conclusion
This study highlights the association between autonomic symptom burden and poor hearing outcomes in SSNHL patients. The findings underscore the importance of evaluating autonomic function during the treatment of SSNHL.</description><subject>autonomic symptom burden</subject><subject>COMPASS 31</subject><subject>sudden hearing loss</subject><issn>0194-5998</issn><issn>1097-6817</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp1kEFLwzAYhoMobk7xH0huCtKZpCZpjnOoE8Z2mJ5DmqQu0jYzaRn792ZsevP0vXw8vLw8AFxjNMYIkQe_bseUoRMwxEjwjBWYn4IhwuIxo0IUA3AR4xdCiDHOz8Eg5wXnJKdDsJjE6LVTnfMt9BWc9J1vfeM0XO2aTecb-NQHY1u4dd0arnqzzyvbRh9ca_ugajizKuVPOPcxXoKzStXRXh3vCHy8PL9PZ9l8-fo2ncwznWOCMkaQ4YQyqhEpkKEmPTRKS7ExQgtbcq2FQlYRwkpLacUFMXkpGGHCMGHzEbg79G6C_-5t7GTjorZ1rVrr-yhJkQzgnOYiobcHVIc0MNhKboJrVNhJjORenkzyZJKXyJtjaV821vxxv7YScH8Atq62u_965HK22Nf9AOg4d4o</recordid><startdate>202403</startdate><enddate>202403</enddate><creator>Yang, Chao‐Hui</creator><creator>Lin, Wei‐Che</creator><creator>Chen, Wei‐Chih</creator><creator>Luo, Sheng‐Dean</creator><creator>Yang, Ming‐Yu</creator><creator>Hwang, Chung‐Feng</creator><creator>Chen, Shu‐Fang</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4055-1686</orcidid></search><sort><creationdate>202403</creationdate><title>Association of Autonomic Symptom Burden with Sudden Sensorineural Hearing Loss</title><author>Yang, Chao‐Hui ; Lin, Wei‐Che ; Chen, Wei‐Chih ; Luo, Sheng‐Dean ; Yang, Ming‐Yu ; Hwang, Chung‐Feng ; Chen, Shu‐Fang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3120-620d72565c0280d5d620c05991dd9c9eb7cc9a0ea226be55f792d3b96269d69e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>autonomic symptom burden</topic><topic>COMPASS 31</topic><topic>sudden hearing loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, Chao‐Hui</creatorcontrib><creatorcontrib>Lin, Wei‐Che</creatorcontrib><creatorcontrib>Chen, Wei‐Chih</creatorcontrib><creatorcontrib>Luo, Sheng‐Dean</creatorcontrib><creatorcontrib>Yang, Ming‐Yu</creatorcontrib><creatorcontrib>Hwang, Chung‐Feng</creatorcontrib><creatorcontrib>Chen, Shu‐Fang</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Otolaryngology-head and neck surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, Chao‐Hui</au><au>Lin, Wei‐Che</au><au>Chen, Wei‐Chih</au><au>Luo, Sheng‐Dean</au><au>Yang, Ming‐Yu</au><au>Hwang, Chung‐Feng</au><au>Chen, Shu‐Fang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Association of Autonomic Symptom Burden with Sudden Sensorineural Hearing Loss</atitle><jtitle>Otolaryngology-head and neck surgery</jtitle><addtitle>Otolaryngol Head Neck Surg</addtitle><date>2024-03</date><risdate>2024</risdate><volume>170</volume><issue>3</issue><spage>862</spage><epage>869</epage><pages>862-869</pages><issn>0194-5998</issn><eissn>1097-6817</eissn><abstract>Objective
To investigate the autonomic symptom burden in patients with sudden sensorineural hearing loss (SSNHL) and its association with the severity and prognosis.
Study Design
Observational prospective study.
Setting
Tertiary academic medical center.
Methods
Patients diagnosed with SSNHL at a single medical center completed the COMPASS 31 questionnaire, which assesses dysautonomia across 6 domains with 31 questions. A total COMPASS 31 score was calculated by summing the scores from each weighted domain. The treatment outcome was evaluated by the percentage of recovery, calculated as the hearing gain in pure tone average (PTA) after treatment divided by the pretreatment PTA difference between the 2 ears. We defined poor recovery as a percentage of recovery <80%.
Results
A total of 63 SSNHL patients were included. The mean COMPASS 31 score was 23.4 (SD 14). Patients with poor recovery had significantly higher COMPASS 31 scores than those with good recovery (mean 26.4 [SD 14.4] vs 16.9 [SD 10.4]; 95% confidence interval [CI] 2‐17). There was a negative association between COMPASS 31 score and both hearing gain (r = −.323, 95% CI −0.082 to −0.529) and percentage of recovery (r = −.365, 95% CI −0.129 to −0.562). Multivariate analyses of independent factors indicate that patients with higher COMPASS 31 scores had a greater risk for poor recovery (OR 1.06 [95% CI 1.003‐1.117]).
Conclusion
This study highlights the association between autonomic symptom burden and poor hearing outcomes in SSNHL patients. The findings underscore the importance of evaluating autonomic function during the treatment of SSNHL.</abstract><cop>England</cop><pmid>37877235</pmid><doi>10.1002/ohn.560</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-4055-1686</orcidid><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0194-5998 |
| ispartof | Otolaryngology-head and neck surgery, 2024-03, Vol.170 (3), p.862-869 |
| issn | 0194-5998 1097-6817 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2881713539 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | autonomic symptom burden COMPASS 31 sudden hearing loss |
| title | Association of Autonomic Symptom Burden with Sudden Sensorineural Hearing Loss |
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