Application Value of Novel Coagulation Markers in Predicting Postoperarative Complications in the Early Stage After Liver Transplantation
ObjectiveTo investigate the relationship between thrombin-antithrombin complex (TAT), plasmin-α 2-plasmininhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (tPAIC) and postoperative complications in the early stage after liver transplantation (L...
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Veröffentlicht in: | Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban 2023-09, Vol.54 (5), p.1024-1029 |
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container_title | Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban |
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creator | Zhang, Xue Chen, Simin Guo, Jun Zhang, Zhongwei Hu, Hai Yang, Jiayin Kang, Yan |
description | ObjectiveTo investigate the relationship between thrombin-antithrombin complex (TAT), plasmin-α 2-plasmininhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (tPAIC) and postoperative complications in the early stage after liver transplantation (LT). MethodsWe analyzed the perioperative clinical data, including plasma TAT, PIC, sTM, and tPAIC, of 130 post-LT patients admitted to the intensive care unit (ICU), West China Hospital, Sichuan University between December 2021 and November 2022. Patients were divided into two groups, a complication group and a non-complication group, according to whether they experienced complications of Clavien-Dindo (CD) grade Ⅲb and above within 30 days after the surgery. Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). P |
doi_str_mv | 10.12182/20230960105 |
format | Article |
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MethodsWe analyzed the perioperative clinical data, including plasma TAT, PIC, sTM, and tPAIC, of 130 post-LT patients admitted to the intensive care unit (ICU), West China Hospital, Sichuan University between December 2021 and November 2022. Patients were divided into two groups, a complication group and a non-complication group, according to whether they experienced complications of Clavien-Dindo (CD) grade Ⅲb and above within 30 days after the surgery. Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). P</description><identifier>ISSN: 1672-173X</identifier><identifier>DOI: 10.12182/20230960105</identifier><language>chi</language><ispartof>Sichuan da xue xue bao. Journal of Sichuan University. 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Yi xue ban</title><description>ObjectiveTo investigate the relationship between thrombin-antithrombin complex (TAT), plasmin-α 2-plasmininhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (tPAIC) and postoperative complications in the early stage after liver transplantation (LT). MethodsWe analyzed the perioperative clinical data, including plasma TAT, PIC, sTM, and tPAIC, of 130 post-LT patients admitted to the intensive care unit (ICU), West China Hospital, Sichuan University between December 2021 and November 2022. Patients were divided into two groups, a complication group and a non-complication group, according to whether they experienced complications of Clavien-Dindo (CD) grade Ⅲb and above within 30 days after the surgery. Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). P</description><issn>1672-173X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqVzMFOAjEUBdAuMIEoOz7gLdmgbScwnSUhGBdqSCTGHXkMb8bG0tbXDomf4F87QeLe1V3cc68QEyVvlVZG32mpC1ktpJLzgRipRalnqizehmKckt1LqZQsKlOOxPcyRmdrzDZ4eEXXEYQGnsOJHKwCtp37rZ6QP4gTWA8bpoOts_UtbELKIRIj9-pE_eL493a2-Z1gjey-4CVjS7BsMjE89pZhy-hTdOjz2d-IqwZdovElr8X0fr1dPcwih8-OUt4dbarJ9QMKXdppY6TRSs-r4h_0B-X6XSc</recordid><startdate>20230901</startdate><enddate>20230901</enddate><creator>Zhang, Xue</creator><creator>Chen, Simin</creator><creator>Guo, Jun</creator><creator>Zhang, Zhongwei</creator><creator>Hu, Hai</creator><creator>Yang, Jiayin</creator><creator>Kang, Yan</creator><scope>7X8</scope></search><sort><creationdate>20230901</creationdate><title>Application Value of Novel Coagulation Markers in Predicting Postoperarative Complications in the Early Stage After Liver Transplantation</title><author>Zhang, Xue ; Chen, Simin ; Guo, Jun ; Zhang, Zhongwei ; Hu, Hai ; Yang, Jiayin ; Kang, Yan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_28808212593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2023</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Zhang, Xue</creatorcontrib><creatorcontrib>Chen, Simin</creatorcontrib><creatorcontrib>Guo, Jun</creatorcontrib><creatorcontrib>Zhang, Zhongwei</creatorcontrib><creatorcontrib>Hu, Hai</creatorcontrib><creatorcontrib>Yang, Jiayin</creatorcontrib><creatorcontrib>Kang, Yan</creatorcontrib><collection>MEDLINE - Academic</collection><jtitle>Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Xue</au><au>Chen, Simin</au><au>Guo, Jun</au><au>Zhang, Zhongwei</au><au>Hu, Hai</au><au>Yang, Jiayin</au><au>Kang, Yan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Application Value of Novel Coagulation Markers in Predicting Postoperarative Complications in the Early Stage After Liver Transplantation</atitle><jtitle>Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban</jtitle><date>2023-09-01</date><risdate>2023</risdate><volume>54</volume><issue>5</issue><spage>1024</spage><epage>1029</epage><pages>1024-1029</pages><issn>1672-173X</issn><abstract>ObjectiveTo investigate the relationship between thrombin-antithrombin complex (TAT), plasmin-α 2-plasmininhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (tPAIC) and postoperative complications in the early stage after liver transplantation (LT). MethodsWe analyzed the perioperative clinical data, including plasma TAT, PIC, sTM, and tPAIC, of 130 post-LT patients admitted to the intensive care unit (ICU), West China Hospital, Sichuan University between December 2021 and November 2022. Patients were divided into two groups, a complication group and a non-complication group, according to whether they experienced complications of Clavien-Dindo (CD) grade Ⅲb and above within 30 days after the surgery. Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). P</abstract><doi>10.12182/20230960105</doi></addata></record> |
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title | Application Value of Novel Coagulation Markers in Predicting Postoperarative Complications in the Early Stage After Liver Transplantation |
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