Application Value of Novel Coagulation Markers in Predicting Postoperarative Complications in the Early Stage After Liver Transplantation

ObjectiveTo investigate the relationship between thrombin-antithrombin complex (TAT), plasmin-α 2-plasmininhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (tPAIC) and postoperative complications in the early stage after liver transplantation (L...

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Veröffentlicht in:Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban 2023-09, Vol.54 (5), p.1024-1029
Hauptverfasser: Zhang, Xue, Chen, Simin, Guo, Jun, Zhang, Zhongwei, Hu, Hai, Yang, Jiayin, Kang, Yan
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container_end_page 1029
container_issue 5
container_start_page 1024
container_title Sichuan da xue xue bao. Journal of Sichuan University. Yi xue ban
container_volume 54
creator Zhang, Xue
Chen, Simin
Guo, Jun
Zhang, Zhongwei
Hu, Hai
Yang, Jiayin
Kang, Yan
description ObjectiveTo investigate the relationship between thrombin-antithrombin complex (TAT), plasmin-α 2-plasmininhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (tPAIC) and postoperative complications in the early stage after liver transplantation (LT). MethodsWe analyzed the perioperative clinical data, including plasma TAT, PIC, sTM, and tPAIC, of 130 post-LT patients admitted to the intensive care unit (ICU), West China Hospital, Sichuan University between December 2021 and November 2022. Patients were divided into two groups, a complication group and a non-complication group, according to whether they experienced complications of Clavien-Dindo (CD) grade Ⅲb and above within 30 days after the surgery. Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). P
doi_str_mv 10.12182/20230960105
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MethodsWe analyzed the perioperative clinical data, including plasma TAT, PIC, sTM, and tPAIC, of 130 post-LT patients admitted to the intensive care unit (ICU), West China Hospital, Sichuan University between December 2021 and November 2022. Patients were divided into two groups, a complication group and a non-complication group, according to whether they experienced complications of Clavien-Dindo (CD) grade Ⅲb and above within 30 days after the surgery. Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). P</description><identifier>ISSN: 1672-173X</identifier><identifier>DOI: 10.12182/20230960105</identifier><language>chi</language><ispartof>Sichuan da xue xue bao. Journal of Sichuan University. 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Yi xue ban</title><description>ObjectiveTo investigate the relationship between thrombin-antithrombin complex (TAT), plasmin-α 2-plasmininhibitor complex (PIC), soluble thrombomodulin (sTM), and tissue plasminogen activator-inhibitor complex (tPAIC) and postoperative complications in the early stage after liver transplantation (LT). MethodsWe analyzed the perioperative clinical data, including plasma TAT, PIC, sTM, and tPAIC, of 130 post-LT patients admitted to the intensive care unit (ICU), West China Hospital, Sichuan University between December 2021 and November 2022. Patients were divided into two groups, a complication group and a non-complication group, according to whether they experienced complications of Clavien-Dindo (CD) grade Ⅲb and above within 30 days after the surgery. Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). 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Journal of Sichuan University. Yi xue ban</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhang, Xue</au><au>Chen, Simin</au><au>Guo, Jun</au><au>Zhang, Zhongwei</au><au>Hu, Hai</au><au>Yang, Jiayin</au><au>Kang, Yan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Application Value of Novel Coagulation Markers in Predicting Postoperarative Complications in the Early Stage After Liver Transplantation</atitle><jtitle>Sichuan da xue xue bao. Journal of Sichuan University. 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Univariate analysis and binary multivariate logistic regression models were used to determine the risk factors for complications within 30 days post-LT. ResultsThe incidence of complications of CD grade Ⅲb and above within 30 days post-LT was 33.1% (43/130). P</abstract><doi>10.12182/20230960105</doi></addata></record>
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title Application Value of Novel Coagulation Markers in Predicting Postoperarative Complications in the Early Stage After Liver Transplantation
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