Positive association of acetylcholinesterase (AChE) with the neutrophil-to-lymphocyte ratio and HbA1c, and a negative association with hydrogen sulfide (H2S) levels among healthy African Americans, and H2S-inhibition and high-glucose-upregulation of AChE in cultured THP-1 human monocytes

The incidence of Alzheimer's disease (AD) is higher in people over the age of 65 and in African Americans (AA). Elevated acetylcholinesterase (AChE) activity has been considered a major player in the onset of AD symptoms. As a result, many FDA-approved AD drugs target AChE inhibition to treat A...

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Veröffentlicht in:	Free radical biology & medicine 2023-11, Vol.209, p.185-190
Hauptverfasser:	Jain, Sushil K., Justin Margret, Jeffrey, Lally, Marissa
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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