PE12 interaction with TLR4 promotes intracellular survival of Mycobacterium tuberculosis by suppressing inflammatory response

Macrophages serve as the primary immune cells responsible for the innate immune defense against Mycobacterium tuberculosis (MTB) infection within the host. Specifically, NLRP3, a member of the NLRs family, plays a significant role in conferring resistance against MTB infection. Conversely, MTB evade...

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Veröffentlicht in:	International journal of biological macromolecules 2023-12, Vol.253, p.127547-127547, Article 127547
Hauptverfasser:	Zhang, Jiajun, Cui, Yingying, Zang, Xinxin, Feng, Tingting, Chen, Fanruo, Wang, Hui, Dang, Guanghui, Liu, Siguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Intracellular survival Mycobacterium tuberculosis NLRP3 PE12 TLR4
Online-Zugang:	Volltext
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