Simple confirmation methods for rare but impaired variants of human flavin-containing monooxygenase 3 (FMO3) found in an updated genome resource databank

Forty-seven new nonsense or missense human flavin-containing monooxygenase 3 (FMO3) variants were recently identified in an updated Japanese population reference panel. Of these, 20 rare single-nucleotide substitutions resulted in moderately or severely impaired FMO3 activity. To easily identify the...

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Veröffentlicht in:	Drug metabolism and pharmacokinetics 2023-12, Vol.53, p.100528-100528, Article 100528
Hauptverfasser:	Shimizu, Makiko, Makiguchi, Miaki, Yokota, Yuka, Shimamura, Erika, Matsuta, Moegi, Nakamura, Yuria, Harano, Mizuki, Yamazaki, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Humans Oxygenases - genetics
Online-Zugang:	Volltext
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