Analytical Performance Evaluation of a 523-Gene Circulating Tumor DNA Assay for Next-Generation Sequencing-Based Comprehensive Tumor Profiling in Liquid Biopsy Samples

Next-generation sequencing (NGS)-based comprehensive tumor profiling from liquid biopsy samples can significantly improve diagnosis and monitoring of tumors when high-quality tissue material is difficult to obtain. In addition, it offers the potential to capture the entire complexity of the tumor, w...

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Veröffentlicht in:	The Journal of molecular diagnostics : JMD 2024-01, Vol.26 (1), p.61-72
Hauptverfasser:	Harter, Johannes, Buth, Eleonora, Johaenning, Janina, Battke, Florian, Kopp, Maria, Zelba, Henning, Schulze, Martin, Koedding, Jiri, Biskup, Saskia
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Circulating Tumor DNA - genetics High-Throughput Nucleotide Sequencing - methods Humans Liquid Biopsy - methods Mutation Neoplasms - diagnosis Neoplasms - genetics
Online-Zugang:	Volltext
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