Anxiogenic doses of rapamycin prevent URB597-induced anti-stress effects in socially defeated mice

•URB597 reduces anxiety-like behaviors in SDS mice.•The anxiogenic dose of URB decreased the absolute number, and the migrating doublecortin cells.•SDS-induced increased Raptor expression in the hippocampus.•URB507 fails to induce anxiolytic effects in mice treated with rapamycin. Repeated exposure...

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Veröffentlicht in:	Neuroscience letters 2024-01, Vol.818, p.137519-137519, Article 137519
Hauptverfasser:	Fusse, Eduardo J., Scarante, Franciele F., Vicente, Maria A., Marrubia, Mariana M., Turcato, Flávia, Scomparin, Davi S., Ribeiro, Melissa A., Figueiredo, Maria J., Brigante, Tamires A.V., Guimarães, Francisco S., Campos, Alline C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anandamide Anxiety-like behavior mTOR Rapamycin Social defeat stress
Online-Zugang:	Volltext
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