A toolbox for mimicking gastrointestinal conditions in children: Design and evaluation of biorelevant dissolution media for mimicking paediatric gastric- and small intestinal conditions

The goal of the present work was to develop an in vitro toolbox to evaluate the oral administration of dosage forms to children of different age groups and under different administration conditions (fasted/fed). Based on current data on the gastrointestinal physiology of children, a set of new biore...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2023-12, Vol.193, p.144-157
Hauptverfasser:	Freerks, Lisa, Arien, Tina, Mackie, Claire, Inghelbrecht, Sabine, Klein, Sandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Child Child, Preschool Fasting Humans Intestine, Small Solubility Stomach
Online-Zugang:	Volltext
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