Ferroptosis: underlying mechanisms and involvement in neurodegenerative diseases

Ferroptosis, a mode of cell death that was recently identified in 2012, is driven by iron-dependent lipid peroxidation and distinct from other mechanisms of cell death such as autophagy and apoptosis. Ferroptosis has the unique features of disruptions in iron equilibrium, iron-induced lipid peroxida...

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Veröffentlicht in:	Apoptosis (London) 2024-02, Vol.29 (1-2), p.3-21
Hauptverfasser:	Wang, Yi, Li, HongJing, He, QianXiong, Zou, Rong, Cai, JinRui, Zhang, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Analysis Anion channels Apoptosis Autophagy Biochemistry Biomedical and Life Sciences Biomedicine Cancer Research Cell Biology Cell Death Central nervous system Degeneration Development and progression Ferroptosis Ferroptosis - genetics Genetic aspects Glutamate Humans Ion channels Iron Lipid Peroxidation Lipids Medical research Medicine, Experimental Metabolic pathways Mortality Nervous system Neurodegenerative diseases Neurodegenerative Diseases - genetics Oncology Pathogenesis Peroxidation Review Reviews Therapeutic applications Toxicity Tumor proteins Virology Zileuton
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