Evaluation of HNF1B, KLK3, ELAC2, TMPRSS2-ERG, and CTNNB1 polymorphisms associated with prostate cancer in samples of patients from HUPE-UERJ

Prostate cancer (PCa) is the leading cause of death among men in 48 countries. Genetic alterations play a significant role in PCa carcinogenesis. For the hypothesis of this research, five unique polymorphisms (SNP) were investigated in different genes that showed to be associated in different ways w...

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Veröffentlicht in:	The Prostate 2024-02, Vol.84 (2), p.166-176
Hauptverfasser:	Menezes, Raphaela Dos Santos, Dornas, Maria Cristina, Campos, Carlos Frederico Ferreira, Rodeiro, Daniela Bouzas, Carrerette, Fabricio Borges, Oliveira, Romulo Vianna, de Souza, Brenda Amaral, Alves de Souza Carvalho, Gabriele, Brito, Ingrid Alexandre de Abreu, Silva, Dayse Aparecida, Damião, Ronaldo, Porto, Luís Cristóvão
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles beta Catenin - genetics Biopsy Carcinogenesis Ethnicity Gene frequency Genetic Predisposition to Disease Genotype Genotyping Haplotypes Hepatocyte Nuclear Factor 1-beta - genetics Humans Kallikreins Kallikreins - genetics Male Minority & ethnic groups Neoplasm Proteins Polymorphism, Single Nucleotide Prostate cancer Prostate-Specific Antigen Prostatic Neoplasms - pathology Single-nucleotide polymorphism Transcriptional Regulator ERG - genetics
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