Cuminum cyminum Ameliorates Urotoxic Effects of Cyclophosphamide by Modulating Antioxidant, Inflammatory Cytokines, and Urinary Bladder Overactivity: In vivo and in Silico Investigations

Interstitial Cystitis (IC) is a chronic inflammatory disease that lacks effective treatment. The present study aimed to investigate the potential of aqueous ethanol extract of Cuminum cyminum (AEECC) on oxidative stress, inflammation and overactivity of urinary bladder induced by cyclophosphamide (C...

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Veröffentlicht in:	Chemistry & biodiversity 2023-12, Vol.20 (12), p.e202301268-n/a
Hauptverfasser:	Anjum, Irfan, Ali, Daanyaal, Bourhia, Mohammed, Chaudhry, Mueen Ahmad, Siddique, Farhan, Bibi, Mehvish, Gaafar, Abdel‐Rhman Z., Zair, Touriya, Khallouki, Farid
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Atropine Bioactive compounds Biocompatibility Bladder Carbachol Cuminum Cyminum Cyclophosphamide Cytokines Drug development Edema Ethanol Extravasation Functional foods & nutraceuticals Glibenclamide Hemorrhage In vivo methods and tests Indomethacin inflammation Inflammatory diseases Interleukin 6 Interstitial cystitis Investigations Nifedipine Nitric oxide Oxidative stress Pain perception Permeability Plant extracts Propranolol Seeds Smooth muscle Toxicity Urinary bladder Weight
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