Glutamatergic abnormalities in the pregenual anterior cingulate cortex in obsessive-compulsive disorder using magnetic resonance spectroscopy: A controlled study

•OCD is connected with abnormalities in the pgACC, which is a part of the CSTC.•We describe disruption of the Glu, Gln, Glx, and GABA metabolism in the pgACC.•A decrease in Glx, Glu, and Gln was observed in the pgACC in OCD.•In OCD we observed positive correlation of Glu and the severity of compulsi...

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Veröffentlicht in:Psychiatry research. Neuroimaging 2023-10, Vol.335, p.111721-111721, Article 111721
Hauptverfasser: Kosová, Eliška, Pajuelo, Dita, Greguš, David, Brunovský, Martin, Stopková, Pavla, Fajnerová, Iveta, Horáček, Jiří
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Sprache:eng
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