Polycomb repressive complex 2 regulates basal cell fate during adult olfactory neurogenesis

Adult neurogenesis occurs in the mammalian olfactory epithelium to maintain populations of neurons that are vulnerable to injury yet essential for olfaction. Multipotent olfactory basal stem cells are activated by damage, although mechanisms regulating lineage decisions are not understood. Using mou...

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Veröffentlicht in:Stem cell reports 2023-11, Vol.18 (11), p.2283-2296
Hauptverfasser: Ko, Tiffany, Choi, Rhea, Issa, Khalil, Gupta, Rupali, Llinas, Edward, Morey, Lluis, Finlay, John B., Goldstein, Bradley J.
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Sprache:eng
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